Outer Bio is building the future of human skin health
We pair machine learning with full-thickness human skin that stays alive for weeks—long enough to discover the next generation of mechanisms and actives.
Our Discovery PLatform
YUNA
/ˈjuːnə/
built on long-lasting, full-thickness human skin.
We’ve brought living human tissue, automated in vitro screening, and machine learning into one integrated system–built to discover the new mechanisms and molecules that move skin health forward.
Our Technology
platform technology
YUNA: Full-thickness human skin, viable for four weeks
Epidermis, dermis, multiple resident cell types, and preserved immune-associated molecular programs — living long enough to watch the biology that matters actually unfold.
Multi-donor datasets from hundreds of individuals across skin types
Many skin research studies rely on tissue from a limited number of donors. Our platform sources skin across ages, races, genders, and Fitzpatrick types, so results reflect the diversity of real human biology.
Automated in vitro phenotype studies
Robot liquid handling and automated assays validate predicted hits against the phenotypes that matter – before anything reaches human tissue.
ML models that find new targets and screen millions of compounds a day
Trained on data from our own human tissue–not public datasets–our models surface novel targets and rank candidates before we ever run an experiment.
YUNA: Full-thickness human skin, viable for four weeks
Epidermis, dermis, multiple resident cell types, and preserved immune-associated molecular programs — living long enough to watch the biology that matters actually unfold.
Discoveries
We discover new mechanisms and molecules.
Most skincare "innovation" recombines the same limited set of molecules: better delivery, bio-identical versions, incremental tweaks. Our platform was built to do something different: identify genuinely new mechanisms of action, and the compounds that drive them, in biology that behaves like real human skin.
We moved beyond outdated and simplified models to find truly novel actives–where an industry built on decades-old ingredients has stalled.
Access to human-relevant skin biology
We partner with biotech, pharma, skincare & cosmetics, and ingredient suppliers.
Not every partner needs a finished ingredient or compound. Some come to us for the platform itself—research collaborations to study their compounds, answer a specific biological question, or de-risk a development decision in tissue that lives long enough to provide a useful answer.
